Hashimoto thyroiditis with an unusual presentation of cardiac tamponade in Noonan syndrome
نویسندگان
چکیده
Noonan syndrome is an autosomal dominant, multisystem disorder. Autoimmune thyroiditis with hypothyroidism is an infrequent feature in patients with Noonan syndrome. A 16-year-old boy was admitted because of chest discomfort and dyspnea; an echocardiogram revealed pericardial effusion. Additional investigations led to a diagnosis of severe hypothyroidism due to Hashimoto thyroiditis. The patient was treated with L-thyroxine at 0.15 mg daily. However, during admission, he developed symptoms of cardiac tamponade. Closed pericardiostomy was performed, after which the patient's chest discomfort improved, and his vital signs stabilized. Herein, we report a case of an adolescent with Noonan syndrome, who was diagnosed with Hashimoto thyroiditis with an unusual presentation of cardiac tamponade.
منابع مشابه
Massive pericardial effusion in a patient with Hashimoto's thyroiditis: histological examination of underlying cardiomyopathy.
An unusual case of a hypothyroid patient with huge pericardial effusion due to Hashimoto's thyroiditis is reported. Cardiac tamponade occurred during admission. Eight hundred milliliters of pericardial effusion was withdrawn by pericardiocentesis. Even after successful replacement of thyroid hormone, she had recurrent effusion two years later. Refractory pericardial effusion is a rare complicat...
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Noonan syndrome is a genetic condition inherited by an autosomally dominant manner, characterised by congenital heart disease, short stature, abnormal facies and the somatic feature of Turner's syndrome, but a normal karyotype. Noonan syndrome affects approximately 1 in 1500 live births. Congenital heart disease occurs in 35-50% of patients diagnosed with noonan syndrome. The most common cardia...
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